Preheat oven to 400 degrees F. Cover a large baking sheet with parchment paper; set aside. In a mixing bowl or stand mixer, combine self-rising flour and Greek yogurt until a thick dough forms.
Roll dough out onto a lightly floured surface into a large rectangle (approximately 10”x14”) then place on prepared baking sheet; set aside.
Add sausage to a large skillet over medium- high heat. Cook, breaking up the meat, until cooked through. Drain excess liquid; set aside.
Spread marinara over dough then top with shredded cheese, pepperoni, cooked sausage and ham.
Bake for 20-22 minutes or until crust is golden brown. Cut into pieces and serve.